Meeting Reports

The Immunology of Ageing

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TheImmunologyOfAgeing

Meeting report from the Euroscicon event: 24th February 2014, London, UK

Meeting Chairs:

Dr Neil A Mabbott, The Roslin Institute& Royal (Dick) School of Veterinary Sciences, University of Edinburgh, UK.

Dr Milica Vukmanovic-Stejic, Senior Research Fellow, UCL Medical School, London, UK.

Author: Ms Mari Pattison

The Roslin Institute& Royal (Dick) School of Veterinary Sciences, University of Edinburgh, UK

Editors: Dr Shara Cohen and Dr Astrid Englezou

This meeting report discusses immunological changes which occur during ageing. Topics include B cell repertoire changes, Natural Killer cells and immunosurveillance, cytomegalovirus and coronary heart disease, antigen sampling in the mucosal immune system, age-related macular degeneration, NF-κB dysregulation, and regulatory proteolysis.

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Contents

INTRODUCTION

Old B cells, what are the chances they will help us

Effects of ageing on antigen sampling in the mucosal immune system.

Para-inflammation and age-related macular degeneration.

Lymphocyte proliferation, ageing and the regulatory proteolysis of key proteins.

Effects of melatonin on the age-dependent dysregulation of the NF-KB/NLRP3 activation during sepsis.

Ageing of the immune system – role of CMV for coronary heart disease.

Old before our time Cytomegalovirus establishes the rudimentary signs of an ageing immune system even in young and healthy adults.

Insights into maintaining immunosurveillance in advanced age: killer inhibitory receptors (KIR) haplogroups A and B track with natural killer cells and cytokine profile in oct/nonagenarians in Belfast Elderly Longitudinal Free-living Aging Study (BELFAST)

CONCLUSION.

REFERENCES.

BIOGRAPHIES.

POSTER PRESENTATIONS.

FUNCTIONAL CELLULAR IMAGING OF IMMUNE RESPONSES DURING AGEING USING INTRAVITAL MULTIPHOTON MICROSCOPY.

EFFECTS OF MELATONIN ON THE AGE-DEPENDENT DYSREGULATION OF THE NF-kB/NLRP3 ACTIVATION DURING SEPSIS.

HUMORAL AND CELLULAR IMMUNE RESPONSES TO PRIMARY JAPANESE ENCEPHALITIS VACCINATION IN THE ELDERLY COMPARED TO THE YOUNG.

DETECTION OF INFECTION IN FRAIL ELDERLY: A CHALLENGE.

PETRI NETS COMPUTER MODEL OF IMMUNE SYSTEM OPENS OPPORTUNITY TO STUDY EFFECTS OF AGEING, AUTISMS AND FEVER.

 

  • Format: Kindle Edition
  • File Size: 1182 KB
  • Print Length: 36 pages
  • Simultaneous Device Usage: Unlimited
  • Publisher: HONNAO (29 Jun 2014)
  • Sold by: Amazon Media EU S.à r.l.
  • Language: English
  • ASIN: B00LELLEEK

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